From: The Pertussis resurgence: putting together the pieces of the puzzle
Study year | Study location/name | Design and methods | Number of participants | Comments. |
---|---|---|---|---|
1985 [18] | Sweden, Stockholm | Double blind placebo controlled (compared two Japanese aP vaccines) | 3801 |
No wP control group. 2 dose schedule |
1991 [66] |
Sweden GÖteborg | Double blind placebo controlled (compared DT/DTP) | 3450 |
No wP control 3 dose schedule. |
1992 [67] | Germany, Mainz | Passive monitoring of household contacts | 360 contacts | 3 dose schedule |
1992 [68] | Sweden, Stockholm | Double blind placebo controlled (two-compenent aP/five component aP/wP/DT) | 24,336 |
wP control – (Conaught) 3 dose schedule |
1992 [69] | Italy |
Double blind placebo controlled (aP/wP/DT) | 14,751 |
wP control – (Conaught) 3 dose schedule |
1993 [70] | Germany, Munich |
Case control study (aP/wP/DT/no vaccine) | 16780 | 3 dose schedule |
1990 [71] | Senegal |
-Double blind placebo controlled -Household contact (aP/wP) | 4181 |
No placebo control 3 dose schedule |
Late 90′s [72] | Germany, Erlangen |
Prospective study, 2 groups randomized to aP or wP, third group (not randomized) received DT. | 4 dose schedule |