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Table 2 Site of detection of arboviruses in maternal, fetal annexes, and in different neonatal samples according to virus type

From: Arboviruses and pregnancy: are the threats visible or hidden?

 

Site of detection of RNA

Virus

Mothers

Fetal annexes

Fetus or neonates

ZIKV

Saliva, urine, blood (whole blood, serum, plasma), anal fluid, cervical mucus, vaginal fluid, breast milk, solid organ transplantation, CSF

Amniotic fluid, placenta, membranes, umbilical cord

Cord blood, urine, neonatal blood, CSF, brain

DENV

Breast milk, seminal fluid, saliva, urine, blood, solid organ transplantation, CSF

Amniotic fluid, placenta, umbilical cord

Neonatal blood, urine

JEV

No data

Placenta

Brain, liver

WNV

Blood, serum, urine, brain, CSF, milk

Placenta, umbilical cord

Blood

YFV

Blood

No data

Serum samples

CHIKV

Breast milk, seminal fluid, saliva, urine, blood, amniotic fluid, placenta, membranes, CSF

Amniotic fluid, placenta

Blood

VEEV

Blood, throat swabs, human serum

Amniotic fluid

Brain tissue from aborted and stillborn human fetuses

OROV

blood

No data

No data

  1. The identification of the virus at a site does not mean that it can be considered as a possible source of contamination (e.g., ZIKV has been found in breast milk without being a confirmed mode of neonatal contamination)
  2. CHIKV Chikungunya virus, CSF cerebrospinal fluid, DENV Dengue virus, JEV Japanese encephalitis virus, OROV Oropouche orthobunyavirus, VEEV Venezuelan equine encephalitis virus, WNV West Nile virus, YFV Yellow fever virus, ZIKV Zika virus