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Table 3 Summary of individual findings for Malaria

From: Imported diseases in travellers presenting to the emergency department after a stay in a malaria-endemic country: a retrospective observational study

 

Number of patients

Malaria number (%)

Sensitivity %

(95% CI)

Specificity %

(95% CI)

Positive LR

(95% CI)

Negative LR

(95% CI)

Symptoms

 Fever

253

40 (15.8)

97.50 (86.84—99.94)

7.04 (3.99—11.35)

1.05 (0.99—1.12)

0.36 (0.05—2.61)

 Isolated fever a

253

40 (15.8)

2.50 (0.06—13.16)

97.18 (93.97—98.96)

0.89 (0.11—7.17)

1 (0.95—1.06)

 Headache

253

40 (15.8)

75.00 (58.80—87.31)

44.13 (37.35—51.08)

1.34 (1.08—1.66)

0.57 (0.32—0.99)

 Resporatory tract symptoms

253

40 (15.8)

12.50 (4.19—26.80)

63.38 (56.52—69.86)

0.34 (0.15—0.79)

1.38 (1.18—1.61)

 ENT symptoms

253

40 (15.8)

5.00 (0.61 -16.92)

78.87 (72.77—84.15)

0.24 (0.06—0.94)

1.20 (1.09—1.33)

 Abdominal pain

253

40 (15.8)

20.00 (9.05—35.65)

76.53 (70.25—82.05)

0.85 (0.44—1.66)

1.05 (0.88—1.24)

 Anorexia

253

40 (15.8)

37.50 (22.73—54.20)

43.19 (36.44—50.14)

0.66 (0.44—1.00)

1.45 (1.09—1.92)

 Diarrhea

253

40 (15.8)

17.50 (7.34—32.78)

66.67 (59.90—72.96)

0.52 (0.26—1.06)

1.24 (1.04—1.47)

 Dysuria/urinary frequency

253

40 (15.8)

7.50 (1.57—20.39)

92.96 (88.65—96.01)

1.06 (0.32—3.51)

1.00 (0.90—1.09)

 Myalgia

253

40 (15.8)

55.00 (38.49—70.74)

59.15 (52.23—65.82)

1.35 (0.97—1.86)

0.76 (0.53—1.09)

 Arthralgia

253

40 (15.8)

25.00 (12.69—41.20)

79.34 (73.28 -84.57)

1.21 (0.67—2.20)

0.95 (0.78—1.14)

Laboratory findings

 Anaemiab

253

40 (15.8)

17.50 (7.34—32.78)

84.51 (78.94—89.09)

1.13 (0.54—2.37)

0.98 (0.84—1.14)

 Hyperbilirubinemia c

246

40 (16.3)

35.00 (20.63—51.68)

91.26 (86.54—94.74)

4.01 (2.17—7.38)

0.71 (0.57—0.90)

 Thrombocytopenia d

250

40 (16.0)

77.50 (61.55—89.16)

87.14 (81.85—91.35)

6.03 (4.08—8.90)

0.26 (0.14—0.46)

 Splenomegaly on ultrasound

138

19 (13.8)

26.32 (9.15—51.20)

90.76 (84.06—95.29)

2.85 (1.11—7.29)

0.81 (0.62—1.07)

  1. CI Confidence interval, LR Likelihood ratio, ENT Ear nose throat
  2. a fever without focal signs or symptoms
  3. b Hemoglobin level below 12 g/dl in women and below 14 g/dl in men
  4. c Total bilirubin level exceeding 1.18 mg/dl
  5. d Platelet count below 150 × 10^9/l