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Table 2 Cases of fecal colonization with extended-spectrum beta-lactamase-producing Escherichia coli linked to traveling to India (n = 220)

From: Colonization with extended-spectrum beta-lactamase-producing Escherichia coli and traveler’s diarrhea attack rates among travelers to India: a systematic review and meta-analysis

Travelers’ country of origin

Total cases

Number of cases

Study period/diagnosis year

Organisms identified

TD during/after trip

Group of CTX-M beta-lactamase (resistance genes)

Reference: First author (year)

Comment

Finland

8

8

2009–2010

Escherichia coli, Salmonella and Campylobacter

Yes

NR

Kantele (2021) [54]

-

USA

7

1

2017–2019

Escherichia coli

Yes

CTX-M-15 and NDM-5

Mellon (2020) [55]

Carbapenemase-producing carbapenem-resistant Enterobacterales was also detected

2

2009–2010

Escherichia coli

-

CTX-M-14 and CTX-M-15

Weisenberg (2012)[56]

-

4

2011

Escherichia coli

-

NR

Islam (2012) [57]

Escherichia coli urinary tract infections in children < 2 years of age

Germanya

69

58

2013–2014

Escherichia coli

Yes (for some patients)

-

Miranda (2016) [58]

All patients had gastrointestinal complaints including TD. Data on pre-travel ESBL-PE carrier status were not available

11

2013–2014

Escherichia coli

-

CTX-M-15 and CTX-M-27

Lubbert (2015) [59]

Gastroenteritis was a risk factor

Netherlandsa

20

20

2012–2013

Escherichia coli

Yes (for some patients)

CTX-M-15

Reuland (2016) [60]

Not specified whether all cases had TD

Japan

10

10

2011–2012

Escherichia coli

Yes

CTX-M-15

Yaita (2014) [61]

-

Denmark

3

3

2011

Escherichia coli

-

NR

Lausch (2013) [62]

-

Spain

5

5

2005–2006

Escherichia coli

Yes

CTX-M-15

Guiral (2011) [63]

-

Sweden

18

7

2007–2009

Escherichia coli

-

CTX-M-15

Tangden (2010) [64]

-

11

2007–2008

Escherichia coli

Yes

CTX-M-15

Tham (2010) [65]

-

Canada

80

14

2004–2006

Escherichia coli

-

CTX-M-15

Laupland (2008) [66]

-

66

2012–2014

Escherichia coli

-

CTX-M-15 in 88% (58/66)

Peirano (2017) [67]

Use of antibiotics while in India increased the risk of acquiring ESBL-producing E. coli

  1. Definition of abbreviations: TD Traveler’s diarrhea, ESBL Extended-spectrum beta-lactamase, USA United States of America, NR Not reported
  2. aNot all ESBL-PE strains in these studies were E. coli