Table 1 General features of included papers
From: Mass drug administration for endemic scabies: a systematic review
Author | Year | Setting | Population Size (nearest 100) | Alternative Treatment for Individuals with Contraindications | Further Treatment for Individuals with Clinical Scabies | Drug Delivered | Baseline Scabies Prevalence | Months after MDA for follow up Examination | Scabies Prevalence after MDA |
|---|---|---|---|---|---|---|---|---|---|
Andrews [13] | 2009 | Rural Australia | 5000 | All Eligible | No | Topical Permethrin | 16.10% | 12 months | 13.4% |
Bockarie [34] | 2000 | Rural Papa New guinea | Arm 1–30 Arm 2–60 | No | No | Arm 1 -Oral Ivermectin Arm 2- No treatment | Arm 1–87% Arm 2–52% | 5 months | Arm 1–26% Arm 2–60% |
Carapetis [33] | 1997 | Rural Australia | 200 | No | No | Topical Permethrin | 25% | 1 month | 6% |
Haar [28] | 2014 | Rural Fiji | Cluster 1: 600 Cluster 2: 700 | Yes | No | Cluster 1- Oral Ivermectin Cluster 2- Topical Benzyl Benzoate | Cluster 1–23.7%, Cluster 2–37.9% | Cluster 1: 24 days, Cluster 2: 28 days | Cluster 1–20.0% Cluster 2–9.5% |
Kearns [32] | 2015 | Rural Australia | 1200 | Yes | Yes | Oral Ivermectin | 4% | 18 months | 2% |
Lawrence [27] | 2005 | Rural Solomon Islands | 1600 | Yes | Yes | Oral Ivermectin | 20% | 24 months | 1% |
Leppard [30] | 2000 | Rural Tanzania | 1200 | All Eligible | Yes | Oral Ivermectin | 71% | 12 weeks | 0% |
Marks [25] | 2019 | Rural Solomon Islands | Arm 1–700 Arm 2–700 | Yes | Yes | Arm 1- Oral Ivermectin Arm 2- Oral Ivermectin plus Azithromycin | Arm 1–11.8% Arm 2–9.2% | 12 months | Arm 1–1.0% Arm 2–0.7% |
Martin [31] | 2018 | Rural Tanzania | 4000 | Yes | No | Oral Ivermectin | 4.4% | 12 months | 0.84% |
Romani 2015 [29] | 2015 | Rural Fiji | Arm 1–800 Arm 2–500 Arm 3–700 | Yes | Yes | Arm 1- Standard care (affected people & their household contacts) Arm 2- Topical Permethrin Arm 3- Oral Ivermectin | Arm 1–36.6% Arm 2–41.8% Arm 3–32.1% | 12 months | Arm 1–18.8% Arm 2–15.8% Arm 3–1.9% |
Romani 2019 [26] | 2019 | Rural Solomon Islands | 1400 | Yes | No | Oral Ivermectin and Oral Azithromycin | 18.70% | 12 months | 2.3% |
Taplin [35] | 1991 | Rural Panama | 800 | No | No | Topical Permethrin | 33% | 1 month | 2.5% |