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Table 4 Diagnostic accuracy of Leptospira IgM ELISA assay (PanBio, Queensland, Australia) using acute sera specimen, in comparison to real-time PCR (qPCR)

From: Leptospirosis infections among hospital patients, Sarawak, Malaysia

Diagnostic Type

ELISA assay vs qPCR on sera or urine

(95% CI)

ELISA assay vs qPCR on sera only

(95% CI)

Apparent prevalence

16.3 (10.5–23.6)

16.4 (10.6–23.8)

Sensitivity

24.5 (13.3–38.9)

21.1 (6.1–45.6)

Specificity

88.4 (79.7–94.3)

84.3 (76.4–90.5)

Positive predictive value

54.5 (32.2–75.6)

18.2 (5.2–40.3)

Negative predictive value

67.3 (57.8–75.8)

86.6 (78.9–92.3)