From: Leptospirosis infections among hospital patients, Sarawak, Malaysia
Diagnostic Type | Serum-based RDT* | Urine-based RDT* | ||
---|---|---|---|---|
RDT vs qPCR on sera or urine (95% CI†) | RDT vs qPCR on sera (95% CI†) | RDT vs qPCR on sera or urine (95% CI†) | RDT vs qPCR on urine (95% CI†) | |
Apparent prevalence | 48.1 (39.2–57.0) | 48.0 (39.1–57.1) | 30.5 (23.0–38.8) | 30.5 (23.0–38.8) |
Sensitivity | 47.5 (31.5–63.9) | 36.8 (16.3–61.6) | 22.2 (11.2–37.1) | 18.2 (7.0–35.5) |
Specificity | 51.7 (40.8–62.4) | 50.0 (40.2–59.8) | 65.6 (55.2–75.0) | 65.7 (56.0–74.6) |
Positive predictive value | 30.6 (19.6–43.7) | 11.5 (4.7–22.2) | 23.3 (11.8–38.6) | 14.0 (5.3–27.9) |
Negative predictive value | 68.7 (56.2–79.4) | 81.8 (70.4–90.2) | 64.3 (54.0–73.7) | 72.4 (62.5–81.0) |