Immunoinformatics approach for multi-epitope vaccine design against structural proteins and ORF1a polyprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

Table 2 Helper T-cell lymphocyte predicted epitopes of selected proteins based on antigenicity and IFN-γ response

Protein	Peptide	Length	Antigenicity^a	IFN-gamma
S	TRFASVYAWNRKRIS	15 mer	0.4963	0.7315567
	FQTLLALHRSYLTPG	15 mer	0.5789	0.26071055
	QPYRVVVLSFELLHA	15 mer	0.9109	0.60855322
M	SRTLSYYKLGASQRV	15 mer	0.5731	0.09462399
M	LVGLMWLSYFIASFR	15 mer	0.5535	0.20134879
ORF1a	VSTQEFRYMNSQGLL	15 mer	0.4972	0.97632046
	AALGVLMSNLGMPSY	15 mer	0.8521	0.11429986
	TLNGLWLDDVVYCPR	15 mer	0.4558	0.04915351
	AYESLRPDTRYVLMD	15 mer	0.5553	0.30777655
	SAGIFGADPIHSLRV	15 mer	0.5839	0.24837266
	MFTPLVPFWITIAYI	15 mer	0.6806	0.1415124

ISSN: 2055-0936