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Predisposition to severe disease
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Obesity
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More severe symptoms of COVID-19; requirement for complex ICU management; poorer clinical outcomes
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Diabetes
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Increased clinical severity and mortality
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Access to routine medical care
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COPD
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Cancellation of smoking cessation clinics
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Cystic fibrosis
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Decreased access to multidisciplinary care and transplantation
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Cancer
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Necessity to defer chemotherapy in some cases
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Chronic kidney disease
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Infection risk in dialysis units; decreased access to renal transplantation
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Mental health disorders
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Barriers to accessing outpatient care
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Influence of chronic medications
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Hypertension
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Controversy around use of RAAS blockers
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Autoimmune disease
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Immunosuppressant drugs predispose to infection
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Chronic kidney disease
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Immunosuppressant drugs predispose to infection
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Negative effects of pandemic lockdown
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Obesity
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Restrictions on physical activity; excessive caloric intake
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Mental health disorders
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Social isolation; heightened anxiety; sleep disturbance; reduced capacity of psychotic patients to adhere to public health advice
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