Table 3 Multivariable analysis of rifampicin-resistant among the total Mycobacterium tuberculosis cases using GeneXpertâ„¢ MTB/RIF assay, in Adigrat General Hospital
Variables | Pattern of RIF | Total N (%) | AOR (95% CI) | P-value | |
|---|---|---|---|---|---|
Sensitive N (%) | Resistant N (%) | ||||
Sex | |||||
 Female | 535 (89.8) | 61 (10.2) | 596 (41.2) | a |  |
 Male | 779 (91.6) | 71 (8.4) | 850 (58.8) | 0.74 (0.5–1.09) | 0.13 |
Residence | |||||
 Urban | 1151 (90.9) | 115 (9.1) | 1266 (87.5) | a |  |
 Rural | 163 (90.6) | 17 (9.4) | 180 (12.5) | 1.10 (0.61–1.99) | 0.74 |
Age (Years) | |||||
  ≤ 14 | 41 (93.2) | 3 (6.8) | 44 (3.0) | a |  |
 15–29 | 376 (95.7) | 17 (4.3) | 393 (27.2) | 1.12 (0.37–3.36) | 0.84 |
 30–44 | 386 (91.9) | 34 (8.1) | 420 (29.1) | 0.52 (0.16–1.53) | 0.23 |
 45–59 | 225 (87.2) | 33 (12.8) | 258 (17.8) | 0.54 (0.18–1.62) | 0.27 |
 60–74 | 205 (87.2) | 30 (12.8) | 235 (16.3) | 0.53 (0.17–1.60) | 0.26 |
 75–89 | 78 (83.9) | 15 (16.1) | 93 (6.4) | 1.48 (0.46–4.74) | 0.51 |
  ≥ 90 | 3 (100) | 0 | 3 (0.2) |  |  |
Reason for diagnosis | |||||
 Presumptive TB | 1085 (91.3) | 103 (8.7) | 1188 (82.1) | a |  |
 Presumptive DR TB | 229 (88.8) | 29 (11.2) | 258 (17.9) | 8.92 (5.81–13.69) | < 0.01b |
Presumptive DR-TB | |||||
 New | 1256 (90.7) | 129 (9.3) | 1385 (95.7) | a |  |
 Relapse | 30 (96.8) | 1 (3.2) | 31 (2.2) | 0.32 (0.02–4.71) | 0.41 |
 Failure | 26 (96.3) | 1 (3.7) | 27 (1.9) | 0.16 (0.01–1.85) | 0.14 |
 Lost to follow-up | 2 (66.7) | 1 (33.3) | 3 (0.2) | 0.16 (0.01–2.49) | 0.19 |
Site of presumptive TB | |||||
 Pulmonary | 1283 (90.7) | 131 (9.3) | 1414 (97.8) | a |  |
 Extra-pulmonary | 31 (96.8) | 1 (3.2) | 32 (2.2) | 0.62 (0.22–1.76) | 0.37 |
HIV status | |||||
 Negative | 1036 (91.8) | 92 (8.2) | 1128 (78.1) | a | . |
 Positive | 145 (84.8) | 26 (15.2) | 171 (11.8) | 1.97 (1.13–3.44) | 0.02b |
 Unknown | 133 (90.5) | 14 (9.5) | 147 (10.1) | 0.88 (0.45–1.72) | 0.72 |
Year of Diagnosis | |||||
 2015 | 123 (86.7) | 19 (13.4) | 142 (9.8) | 2.24 (1.19–4.24) | 0.01 |
 2016 | 310 (91.4) | 29 (8.6) | 339 (23.5) | 0.91 (0.53–1.55) | 0.72 |
 2017 | 386 (90.8) | 39 (9.2) | 425 (29.4) | 1.20 (0.74–1.96) | 0.47 |
 2018 | 495 (91.7) | 45 (8.3) | 540 (37.3) | a |  |