Table 2 Trends of positive M. tuberculosis among presumptive TB patients diagnosed in Adigrat General Hospital using GeneXpertâ„¢ MTB/RIF assay
Variables | M. tuberculosis result by GeneXpertâ„¢ | Total | AOR (95% CI) | P-value | |
|---|---|---|---|---|---|
Detected (%) | Not-Detected (%) | ||||
Sex | |||||
 Female | 596 (24.0) | 1893 (76.0) | 2489 (41.9) | a |  |
 Male | 850 (24.6) | 2605 (75.4) | 3455 (58.1) | 0.99 (0.88–1.12) | 0.86 |
Residence | |||||
 Urban | 1266 (24.7) | 3855 (75.3) | 5121 (86.2) | a |  |
 Rural | 180 (21.9) | 643 (78.1) | 823 (13.8) | 1.08 (0.90–1.29) | 0.41 |
Age (Years) | |||||
  ≤ 14 | 44 (18.6) | 192 (81.4) | 236 (3.9) | 2.38 (0.299–18.95) | 0.41 |
 15–29 | 393 (25.1) | 1175 (74.9) | 1568 (26.4) | 3.26 (0.42–25.29) | 0.26 |
 30–44 | 420 (26.0) | 1200 (74.0) | 1620 (27.3) | 3.66 (0.47–28.39) | 0.22 |
 45–59 | 258 (23.3) | 849 (76.7) | 1107 (18.6) | 3.81 (0.49–29.67) | 0.20 |
 60–74 | 235 (22.6) | 804 (77.4) | 1039 (17.4) | 3.64 (0.47–28.32) | 0.22 |
 75–89 | 93 (25.7) | 269 (74.3) | 362 (6.1) | 4.08 (0.52–32.05) | 0.18 |
 90 | 3 (25.0) | 9 (75.0) | 12 (0.3) | a |  |
Reason for diagnosis | |||||
 Presumptive TB | 1188 (23.6) | 3839 (76.4) | 5027 (84.6) | a |  |
 Presumptive DR TB | 258 (28.1) | 659 (71.9) | 917 (15.4) | 1.63 (1.40–1.90) | < 0.01b |
Presumptive DR-TB | |||||
 New | 1385 (23.3) | 4348 (73.1) | 5733 (96.4) | a |  |
 Relapse | 31 (29.5) | 74 (70.5) | 105 (1.8) | 2.69 (0.73–10.04) | 0.14 |
 Failure | 27 (31.0) | 60 (69.0) | 87 (1.4) | 1.68 (0.489–5.80) | 0.41 |
 Lost to follow- up | 3 (15.8) | 16 (84.2) | 19 (0.4) | 2.79 (0.76–10.23) | 0.12 |
Site of presumptive TB | |||||
 Pulmonary | 1414 (24.3) | 4405 (75.7) | 5819 (97.9) | a |  |
 Extra-pulmonary | 32 (25.6) | 92 (74.4) | 125 (2.1) | 0.70 (0.48–1.03) | 0.70 |
HIV status | |||||
 Negative | 1128 (23.7) | 3633 (76.3) | 4761 (80.0) | a |  |
 Positive | 171 (33.3) | 342 (66.7) | 513 (8.7) | 1.67 (1.35–2.07) | < 0.01b |
 Unknown | 147 (21.9) | 523 (78.1) | 670 (11.3) | 0.97 (0.77–1.21) | 0.77 |
Year of Diagnosis | |||||
 2015 | 142 (23.5) | 462 (76.5) | 604 (10.2) | 0.75 (0.61–0.93) | 0.08 |
 2016 | 339 (22.9) | 1140 (77.1) | 1479 (24.9) | 0.63 (0.54–0.74) | < 0.01 |
 2017 | 425 (22.7) | 1447 (77.3) | 1872 (31.5) | 0.65 (0.56–0.75) | < 0.01 |
 2018 | 540 (27.1) | 1449 (72.9) | 1989 (33.4) | a |  |