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Table 5 Tafenoquine for malaria chemoprophylaxis [81,82,83,84]

From: 2018 in review: five hot topics in tropical medicine

Trial type / duration Sample size Regions / species Placebo Efficacy
RCT/6 months [81] 615 soldiers Timor / Australia P. falciparum and P. vivax No N/A – 4 cases in TQ arm
RCT/15 weeks [82] 123 Adults Kenya P. falciparum Yes 86%
RCT/12 weeks [83] 231 Adults Ghana P. falciparum Yes 87% (equivalent to mefloquine)
Experimental exposure to P. falciparum [84]. 16 Adults (4 controls) Australia P. falciparum Yes 100%