Table 5 Tafenoquine for malaria chemoprophylaxis [81,82,83,84]
Trial type / duration | Sample size | Regions / species | Placebo | Efficacy |
|---|---|---|---|---|
RCT/6 months [81] | 615 soldiers | Timor / Australia P. falciparum and P. vivax | No | N/A – 4 cases in TQ arm |
RCT/15 weeks [82] | 123 Adults | Kenya P. falciparum | Yes | 86% |
RCT/12 weeks [83] | 231 Adults | Ghana P. falciparum | Yes | 87% (equivalent to mefloquine) |
Experimental exposure to P. falciparum [84]. | 16 Adults (4 controls) | Australia P. falciparum | Yes | 100% |