Travelers’ diarrhea: update on the incidence, etiology and risk in military and similar populations – 1990-2005 versus 2005–2015, does a decade make a difference?

Table 3 TD associated outcomes (‘90 – ‘15)

Outcome	All years			1990–2005			2006–2015
Outcome	Median	IQR	Min, Max	Median	IQR	Min, Max	Median	IQR	Min, Max
Pre-treatment symptoms, days	1.4	1.1, 2.0	0.3, 4.0	1.4	1.1, 1.7	0.3, 4.1	2.0	1.0, 3.0	1.0, 3.3
Post-treatment symptoms, days	1.5	1.1, 1.9	0.6, 2.2	1.4	0.8, 1.8	0.6, 2.2	1.8	–	1.5, 2.0
- TLUS (abx + loperamide), hrs	9.6	8.2, 11.5	8.2, 11.5	11.5	–	–	8.9	–	8.2, 9.6
- TLUS (abx – loperamide), hrs	21.8	11.0, 43.2	11.0, 43.2	16.4	–	11.0, 21.8	43.2	–	–
Prob. Receiving Abx, %*	57.0	19.0, 91.0	3.0, 100.0	79.0	–	–	44.0	15.0, 96.0	3.0, 100.0
Prob. Receiving loperamide, %*	85.0	27.0, 88.0	17.0, 90.0	–	–	–	85.0	27.0, 88.0	17.0, 90.0
Prob. Receiving IV fluids, %*	15.0	6.0, 19.0	0.0, 33.0	12.0	0.0, 15.0	0.0, 15.0	17.0	6.0, 23.0	5.0, 33.0
Prob. SIQ or incapacitation, %*	21.0	13.0, 34.0	3.0, 55.0	16.0	5.0, 46.0	3.0, 55.0	23.0	13.0, 34.0	4.0, 39.0
Prob. Hospital admission, %	3.0	1.0, 13.0	0.0, 17.0	11.0	–	10.0, 13.0	2.0	1.0, 10.0	0.0, 17.0
Symptom duration in those not seeking treatment, days	3.0	2.4.0, 3.5.0	1.0, 4.3.0	3.0.0	2.5, 3.8	2.1, 4.3	2.9	1.8, 3.6	1.0, 3.8

TLUS – time to last unformed stool
SIQ – sick in quarters
*among those seeking care
Outcomes of interest, including those reflecting the morbidity of diarrheal illness, were compared. Outcomes were compared from all years, from studies included in the prior systematic review (1990–2005), and from studies performed since that time (2006–2015)