Efficacy of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Nepal

Table 1 Outcomes of Therapeutic efficacy studies (TES) of artemether-lumefantrine in P. falciparum cases

Districts/study year	Kailali		Kanchanpur		Jhapa		Total
Districts/study year	2013	2014	2013	2014	2013	2014	Total
TES outcomes
Total P. falciparum Screened	46	22	9	5	13	11	106
TES enrollment cases	13	6	7	1	1	0	28
Lost to follow up/Drop out	3	0	0	0	1	0	4
TES completed	10	6	7	1	0	0	24
Adequate Clinical and Parasitological Response (ACPR)	9	6	7	1			23
Early Treatment Failure (ETF)	0	0	0	0			0
Late Treatment Failure (LTF)	1	0	0	0			1

Note: None of the patients who were followed up for 28 days developed any adverse events. Of the 24, five patients were afebrile in day 3 and 19 became afebrile on day 2. Out of 24 patients, 21 had cleared parasitemia on day 3 and three cleared parasitemia on day 7 and one remained parasitemic until 14 days

ISSN: 2055-0936