Epidemiology of multidrug-resistant tuberculosis (MDR-TB) in Ethiopia: a systematic review and meta-analysis of the prevalence, determinants and treatment outcome

Girum, Tadele; Muktar, Ebrahim; Lentiro, Kifle; Wondiye, Habtamu; Shewangizaw, Misgun

doi:10.1186/s40794-018-0065-5

Tropical Diseases, Travel Medicine and Vaccines

Table 1 Characteristics of studies included in the review

From: Epidemiology of multidrug-resistant tuberculosis (MDR-TB) in Ethiopia: a systematic review and meta-analysis of the prevalence, determinants and treatment outcome

Studies included in the review	Study area	Study population	Study design	Study period	No of patients
[16] Demissie et al. 1997	Addis Ababa	New PTB patients	Cross-sectional study	1994	167
[17] Gebeyehu, 2001	Arsi Zone	PTB patients	Cross-sectional study	1997–98	195
[18] Bruchfeld, 2002	Addis Ababa	PTB patients	Cross-sectional study	2000	121
(19)Asmamaw et al., 2008	Addis Ababa	New PTB patients	Cross-sectional study	2004–5	173
[20] Meskel et al. 2008	Addis Ababa	Previously treated PTB	Cross-sectional study	2001–2	84
[21] Agonafir, 2010	Addis Ababa	PTB patients	Cross-sectional study	2005–6	107
[22] Abate et al., 2012	Addis Ababa	Previously treated PTB	Retrospective	2004–8	376
[23] Abebe et al. 2012	South western Ethiopia	New PTB patients	Cross-sectional study	2010–11	136
[24] Tessema et al. 2012	North Ethiopia	PTB patients	Cross-sectional study	2009	260
[25] Yimer et al. 2012	ARS major towns	New PTB patients	Cross-sectional study	2008	93
[26] Hussein et al. 2013	Bahirdar, Fitche & Ambo	PTB patients	Cross-sectional study	2011	102
[27] Biadglegne et al.2014	Bahirdar, Gondar & Dessie	TB lymphadenitis	Cross-sectional study	2012	226
[28] Esmael et al. 2014	Eastern ARS	PTB patients	Cross-sectional study	2010–11	230
[29] Daniel et al. 2014	Debre Birhan	PTB patients	Cross-sectional study	2013–14	40
[30] Seyoum et al. 2014	Eastern Ethiopia	New PTB patients	Cross-sectional study	2011–13	357
[31] Tekle et al. 2014	Benishangul & Awi	PTB patients	Cross-sectional study	2013–14	87
[32] Abdella et al., 2015	South western Ethiopia	Previously treated PTB	cross sectional	2012–13	79
[33] Adane et al. 2015	East Gojjam	PTB patients	Cross-sectional study	2011–12	89
[34] Maru et al. 2015	Dessie	PTB patients	Cross-sectional study	2012–13	118
(35)Mekonnen et al. 2015	North Gondar	PTB patients	Cross-sectional study	2014	124
[36] Ali et al. 2016	South Ethiopia	PTB patients	cross sectional	2013	109
[37] Hamussie et al. 2016	Arsi Zone	PTB patients	Cross-sectional study	2013–14	106
[38] Brhane et al., 2017	Jigjiga	PTB patients	cross sectional	NR	98
[39] Mulisa et al. 2015	Oromia Region	MDR & Non MDR TB	Case control study	2013–14	439
[40] Dessalegn et al. 2016	Addis Ababa	MDR & Non MDR TB	Case control study	NR	206
[41] Hirpa et al. 2013	Addis Ababa	MDR & Non MDR TB	Case control study	2011–12	268
[42] Deressa et al. 2014	Addis Ababa	MDR & Non MDR TB	Case control study	2013	384
[43] Assefa et al. 2017	Addis Ababa	MDR & Non MDR TB	Case control study	2013	710
[44] Tadesse et al. 2015	Addis Ababa	MDR & Non MDR TB	cross sectional	2008–11	439
[45] Molalign et al. 2015	Addis Ababa & Gondar	MDR TB	Cohort	2011–14	342
[46] Alene et al. 2016	North west Ethiopia	MDR TB	retrospective cohort	2010–15	242
[47] Getachew et al. 2013	Addis Ababa	MDR TB	retrospective cohort	2011–12	188
[48] Meressa et al. 2015	Addis Ababa	MDR TB	Cohort	2009–14	612
[49] Girum et al. 2017	South Ethiopia	MDR TB	retrospective cohort	2011–16	154

ARS- Amhara Regional state MDR- TB = Multidrug resistant tuberculosis

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ISSN: 2055-0936

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