Fig. 1
From: Vectored immunoprophylaxis: an emerging adjunct to traditional vaccination
Immunoprotection by vectored immunoprophylaxis (VIP). a Identification of an effective broadly-neutralizing antibody (BNA). The most potent of the BNAs is noted with two checkmarks in the graphic. b The genetic sequences of the antibody variable regions are determined. c The genetic sequence for the BNA can then be placed downstream from an appropriate promoter (Prom) within a suitable vector. d The vector can then be administered to the subject in an appropriate tissue platform, such as muscle. The BNA produced by the vector and secreted by the tissue confers the host subject with broad and lasting protection from the targeted pathogen