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Table 1 Incidence ratio ratio’s and mortality in HIV-exposed and –unexposed infants less than 6 months of age

From: Vaccination of HIV-infected pregnant women: implications for protection of their young infants

  Year Incidence (95% CI) per 100 000 Incidence rate ratio (95% CI) Mortality risk
   HIV-exposed HIV-unexposed   
Invasive disease
Streptococcus pneumoniae [6] 2013 57 (46–71) 21 (17–36) 2.7 (2.0–3.7) 1.8 (1.1–2.9)a
Streptococcus agalactiae b [7] 2004–2008 4.5 (3.9–5.1) 2.0 (1.7–2.3) 2.3 (1.9–2.8) -
Lower respiratory tract associated hospitalization
 Respiratory syncytial virus [9] 2010–2011 5003 (4505–5541) 3507 (3244–3787) 1.4 (1.3–1.5) 2.1 (1.1–3.8)c
 Human metapneumovirus [9] 2010–2011 816 (622–1050) 573 (470–692) 1.4 (1.1–2.0) -
  1. aadjusted relative risk ratio in HEU infants (37% [59/175]) versus HIV-unexposed infants (32% [51/228]) for 2009 and 2013; bLess than 3 months of age; cOdd ratio of death in HEU versus HIV-unexposed infants