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Table 1 Incidence ratio ratio’s and mortality in HIV-exposed and –unexposed infants less than 6 months of age

From: Vaccination of HIV-infected pregnant women: implications for protection of their young infants

 

Year

Incidence (95% CI) per 100 000

Incidence rate ratio (95% CI)

Mortality risk

  

HIV-exposed

HIV-unexposed

  

Invasive disease

  Streptococcus pneumoniae [6]

2013

57 (46–71)

21 (17–36)

2.7 (2.0–3.7)

1.8 (1.1–2.9)a

  Streptococcus agalactiae b [7]

2004–2008

4.5 (3.9–5.1)

2.0 (1.7–2.3)

2.3 (1.9–2.8)

-

Lower respiratory tract associated hospitalization

 Respiratory syncytial virus [9]

2010–2011

5003 (4505–5541)

3507 (3244–3787)

1.4 (1.3–1.5)

2.1 (1.1–3.8)c

 Human metapneumovirus [9]

2010–2011

816 (622–1050)

573 (470–692)

1.4 (1.1–2.0)

-

  1. aadjusted relative risk ratio in HEU infants (37% [59/175]) versus HIV-unexposed infants (32% [51/228]) for 2009 and 2013; bLess than 3 months of age; cOdd ratio of death in HEU versus HIV-unexposed infants