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Table 3 Performance of Plasmodium falciparum eba-175 transcript expression compared to gold-standard microscopy for identification of asexual parasitemia

From: Correlating quantitative real-time PCR to rapid diagnostic test and RNA transcript expression in isolated gametocytemia and asexual parasitemia of Plasmodium falciparum malaria

eba-175 transcript expression

Microscopy

Predictive values

Isolated asexual stages (N)

Isolated sexual stages (Gametocytes) (N)

eba-175 Positive

20

12

PPVa = 62.5 %

eba-175 Negative

0

13

NPVb = 100 %

Performance Characteristics

Sensitivityc = 100 %

Specificityd = 52 %

 
  1. apositive predictive value for asexual parasitemia, calculated as (true positives)/(true positives + false positives)
  2. bnegative predictive value for asexual parasitemia, calculated as (true negatives)/(true negatives + false negatives)
  3. csensitivity for asexual parasitemia, calculated as (true positives)/(true positives + false negatives)
  4. dspecificity for asexual parasitemia, calculated as (true negatives)/(true negatives + false positives)