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Table 3 Performance of Plasmodium falciparum eba-175 transcript expression compared to gold-standard microscopy for identification of asexual parasitemia

From: Correlating quantitative real-time PCR to rapid diagnostic test and RNA transcript expression in isolated gametocytemia and asexual parasitemia of Plasmodium falciparum malaria

eba-175 transcript expression Microscopy Predictive values
Isolated asexual stages (N) Isolated sexual stages (Gametocytes) (N)
eba-175 Positive 20 12 PPVa = 62.5 %
eba-175 Negative 0 13 NPVb = 100 %
Performance Characteristics Sensitivityc = 100 % Specificityd = 52 %  
  1. apositive predictive value for asexual parasitemia, calculated as (true positives)/(true positives + false positives)
  2. bnegative predictive value for asexual parasitemia, calculated as (true negatives)/(true negatives + false negatives)
  3. csensitivity for asexual parasitemia, calculated as (true positives)/(true positives + false negatives)
  4. dspecificity for asexual parasitemia, calculated as (true negatives)/(true negatives + false positives)