Advising the immunocompromised traveller: a review of immunocompromise at The London Hospital for Tropical Diseases Travel Clinic between 1st April 2019 and 30th April 2020

Table 1 Types of immunocompromise across the immunocompromised traveller cohort

Immunosuppressive Condition or State			Patients (n)
Primary immunodeficiencies					4
Secondary/Acquired immunocompromise					189
	a. Physiological			81
		Pregnancy	36
		Age ≥ 60	34
		Age ≤ 2	11
	b. Infectious inflammatory condition			33
		Living with HIV	31
		Infectious Liver Disease	2
	c. Immunosuppression for the following conditions			32
		Rheumatological	17
		Neurological	5
		Gastrointestinal	3
		Ophthalmological	3
		SOT	2
		Dermatological	1
		PFAPA Syndrome	1
	d. Malignancy			21
		Solid organ cancer	1
		Haematological cancer	20
	e. Metabolic inflammatory condition			13
		Diabetes mellitus I & II	13
	f. Asplenia/hyposplenia			7
		Sickle cell disease	6
		Coeliac disease	1
	g. Thymic dysfunction			2
		Thymectomy secondary to myasthenia gravis	2
Total					193

Abbreviations: HIV, human immunodeficiency virus; PFAPA, Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis; SOT, solid organ transplant. Categorisation of ICTs into the above groups reflects the most immunocompromising diagnosis or main immunosuppressive therapy responsible for immunosuppression

ISSN: 2055-0936