The use of rotational thromboelastometry parameters in understanding the coagulopathy following hump-nosed viper (Hypnale spp) bites: a preliminary study

Table 1 HNV case scenarios

Age (years)/ Gender	INR <1.4	INTEM-CT (sec)	EXTEM-CT (sec)	FIBTEM-MCF (mm)	Platelet count (×10⁹/ L)	WBCT20	AVS	Summary	Clinical syndrome
70/F	1.04	119	58	15	275	Clotted	Not given	Clotted WBCT20 and normal ROTEM	AKI, NS+, LE+
65/ M	0.97	171	64	12	135				AKI, NS+, LE+
58/ M	1.13	225	61	16	226				NS+, LE+
33/ M	1.01	155	69	16	-				NS+, LE+
13/ M	1.14	170	61	10	-				NS+, LE+
63/ M	0.906	187	55	10	183				NS+, LE+
34/ M	1.03	143	50	12	322				NS+, LE+
59/ M	1.15	170	77	13	-				NS+, LE+
57/ F	1.07	129	56	19	-				NS+, LE+
37/ F	0.99	185	79	14	263				NS+, LE+
56/ M	4.88 ↑	165	97 ↑	18	221	Clotted	Not given	Clotted WBCT20 and abnormal ROTEM.	NS+, LE+
50/ M	1.16	177	90 ↑	11	239				NS+, LE+
40/ M	1.06	130	102 ↑	10	223				NS+, LE+
40/ M	1.00	178	83 ↑	24	-				NS+, LE+
48/ M	1.4	151	83 ↑	12	288				NS+, LE+
50/ M	0.91	257 ↑	64	10	194				AKI, NS+, LE+
57/ M	0.963	2510 ↑	66	13	150				NS+, LE+
31/ M	1.14	389 ↑	77	10	264				NS+, LE+
15/ M	1.17	347 ↑	73	17	267				NS+, LE+
52/ M	1.00	263 ↑	54	17	19 ↓		Given		AKI, NS+, LE+
40/M	1.79 ↑	312 ↑	2285 ↑	3 ↓	122 ↓		Given		NS+, LE+
29/ M	1.06	109	65	9	259	Non-clotted	Not given	Non-clotted WBCT20 and normal ROTEM	NS+, LE+
59/M	1.03	240	70	7	130	Non-clotted	Not given	Non-clotted WBCT20 and normal ROTEM	NS+, LE+

CT Clotting time, EXTEM Extrinsic pathway thromboelastometry, FIBTEM Fibrinolytic pathway thromboelastometry, INR International normalized ratio, INTEM Intrinsic pathway thromboelastometry, MCF Maximum clot firmness, ROTEM Rotational thromboelastometry, WBCT20 Whole blood clotting test
↑Abnormally high, ↓Abnormally low, F= female, LE Local effects, M Male, NS Non-specific effects
(Reference ranges: Platelet count 150-450 ×10⁹/ L; INTEM-CT 100-240 sec; EXTEM-CT 38-79 sec; FIBTEM-MCF 9-25 mm)

ISSN: 2055-0936